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Reduced mGluR5 Activity Modulates Mitochondrial Function

The metabotropic glutamate receptor 5 (mGluR5) is an essential modulator of synaptic plasticity, learning and memory; whereas in pathological conditions, it is an acknowledged therapeutic target that has been implicated in multiple brain disorders. Despite robust pre-clinical data, mGluR5 antagonist...

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Detalles Bibliográficos
Autores principales: Gonzalez-Lozano, Miguel A., Wortel, Joke, van der Loo, Rolinka J., van Weering, Jan R. T., Smit, August B., Li, Ka Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228325/
https://www.ncbi.nlm.nih.gov/pubmed/34199502
http://dx.doi.org/10.3390/cells10061375