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Reduced mGluR5 Activity Modulates Mitochondrial Function
The metabotropic glutamate receptor 5 (mGluR5) is an essential modulator of synaptic plasticity, learning and memory; whereas in pathological conditions, it is an acknowledged therapeutic target that has been implicated in multiple brain disorders. Despite robust pre-clinical data, mGluR5 antagonist...
Autores principales: | Gonzalez-Lozano, Miguel A., Wortel, Joke, van der Loo, Rolinka J., van Weering, Jan R. T., Smit, August B., Li, Ka Wan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228325/ https://www.ncbi.nlm.nih.gov/pubmed/34199502 http://dx.doi.org/10.3390/cells10061375 |
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