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Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway

Vascular calcification is strongly associated with atherosclerotic plaque burden and plaque instability. The activation of extracellular signal-regulated kinase 1/2 (ERK1/2) increases runt related transcription factor 2 (RUNX2) expression to promote vascular calcification. Procyanidin B2 (PB2), a po...

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Detalles Bibliográficos
Autores principales: Liang, Yingquan, Chen, Guilan, Zhang, Feng, Yang, Xiaoxiao, Chen, Yuanli, Duan, Yajun, Yu, Maoyun, Zhang, Shuang, Han, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228429/
https://www.ncbi.nlm.nih.gov/pubmed/34198832
http://dx.doi.org/10.3390/antiox10060916