Cholesteryl Ester Promotes Mammary Tumor Growth in MMTV-PyMT Mice and Activates Akt-mTOR Pathway in Tumor Cells

The association between intratumoral cholesteryl ester (CE) and tumor progression has been reported previously. The objective of our study was to investigate a causal effect of CE on mammary tumor progression. Using MMTV-PyMT (MMTV-polyoma virus middle T) transgenic mice and breast tumor cell MCF-7,...

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Detalles Bibliográficos
Autores principales: Wei, Lengyun, Lu, Xuyang, Weng, Shengmei, Zhu, Shenglong, Chen, Yongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228430/
https://www.ncbi.nlm.nih.gov/pubmed/34201030
http://dx.doi.org/10.3390/biom11060853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228430/
https://www.ncbi.nlm.nih.gov/pubmed/34201030
http://dx.doi.org/10.3390/biom11060853

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