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Inhibition of Phosphatidylinositol 3-Kinase by Pictilisib Blocks Influenza Virus Propagation in Cells and in Lungs of Infected Mice

Influenza virus (IV) infections are considered to cause severe diseases of the respiratory tract. Beyond mild symptoms, the infection can lead to respiratory distress syndrome and multiple organ failure. Occurrence of resistant seasonal and pandemic strains against the currently licensed antiviral m...

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Detalles Bibliográficos
Autores principales: Deinhardt-Emmer, Stefanie, Jäckel, Laura, Häring, Clio, Böttcher, Sarah, Wilden, Janine J., Glück, Brigitte, Heller, Regine, Schmidtke, Michaela, Koch, Mirijam, Löffler, Bettina, Ludwig, Stephan, Ehrhardt, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228449/
https://www.ncbi.nlm.nih.gov/pubmed/34072389
http://dx.doi.org/10.3390/biom11060808