Cargando…
Inhibition of Phosphatidylinositol 3-Kinase by Pictilisib Blocks Influenza Virus Propagation in Cells and in Lungs of Infected Mice
Influenza virus (IV) infections are considered to cause severe diseases of the respiratory tract. Beyond mild symptoms, the infection can lead to respiratory distress syndrome and multiple organ failure. Occurrence of resistant seasonal and pandemic strains against the currently licensed antiviral m...
Autores principales: | Deinhardt-Emmer, Stefanie, Jäckel, Laura, Häring, Clio, Böttcher, Sarah, Wilden, Janine J., Glück, Brigitte, Heller, Regine, Schmidtke, Michaela, Koch, Mirijam, Löffler, Bettina, Ludwig, Stephan, Ehrhardt, Christina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228449/ https://www.ncbi.nlm.nih.gov/pubmed/34072389 http://dx.doi.org/10.3390/biom11060808 |
Ejemplares similares
-
Staphylococcus aureus Lung Infection Results in Down-Regulation of Surfactant Protein-A Mainly Caused by Pro-Inflammatory Macrophages
por: Schicke, Elisabeth, et al.
Publicado: (2020) -
D,L-Lysine-Acetylsalicylate + Glycine (LASAG) Reduces SARS-CoV-2 Replication and Shows an Additive Effect with Remdesivir
por: Jungwirth, Johannes, et al.
Publicado: (2022) -
SARS-CoV-2 Causes Severe Epithelial Inflammation and Barrier Dysfunction
por: Deinhardt-Emmer, Stefanie, et al.
Publicado: (2021) -
The influenza replication blocking inhibitor LASAG does not sensitize human epithelial cells for bacterial infections
por: Wilden, Janine J., et al.
Publicado: (2020) -
Impact of Staphylococcus aureus Small Colony Variants on Human Lung Epithelial Cells with Subsequent Influenza Virus Infection
por: Wilden, Janine J., et al.
Publicado: (2020)