Cargando…

PARP inhibitors in gastric cancer: beacon of hope

Defects in the DNA damage response (DDR) can lead to genome instability, producing mutations or aberrations that promote the development and progression of cancer. But it also confers such cells vulnerable to cell death when they inhibit DNA damage repair. Poly (ADP-ribose) polymerase (PARP) plays a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yali, Zheng, Kun, Huang, Yongbiao, Xiong, Hua, Su, Jinfang, Chen, Rui, Zou, Yanmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228511/
https://www.ncbi.nlm.nih.gov/pubmed/34167572
http://dx.doi.org/10.1186/s13046-021-02005-6