Cargando…

Human SLC46A2 Is the Dominant cGAMP Importer in Extracellular cGAMP-Sensing Macrophages and Monocytes

[Image: see text] Administration of exogenous CDNs to activate the cGAMP-STING pathway is a promising therapeutic strategy to unleash the full potential of cancer immunotherapy. This strategy mirrors the role of endogenous extracellular cGAMP, an immunotransmitter that is transferred from cancer cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Cordova, Anthony F., Ritchie, Christopher, Böhnert, Volker, Li, Lingyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228594/
https://www.ncbi.nlm.nih.gov/pubmed/34235268
http://dx.doi.org/10.1021/acscentsci.1c00440