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The Molecular Basis for Escherichia coli O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability

Bacteriophage-encoded endolysins have been identified as antibacterial candidates. However, the development of endolysins as mainstream antibacterial agents first requires a comprehensive biochemical understanding. This study defines the atomic structure and enzymatic function of Escherichia coli O1...

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Detalles Bibliográficos
Autores principales: Love, Michael J., Coombes, David, Manners, Sarah H., Abeysekera, Gayan S., Billington, Craig, Dobson, Renwick C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228626/
https://www.ncbi.nlm.nih.gov/pubmed/34207694
http://dx.doi.org/10.3390/v13061101