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A Novel Signature of CCNF-Associated E3 Ligases Collaborate and Counter Each Other in Breast Cancer

SIMPLE SUMMARY: The dysregulation of UPS exacerbates the tumor microenvironment and drives malignant transformation. As the largest family of E3 ligases, the SCF(F-boxes) promotes BRCA progression. FBXL8 was recently identified to be a novel SCF E3 ligase that potently promotes BRCA. Here, we profil...

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Detalles Bibliográficos
Autores principales: Chang, Shu-Chun, Hung, Chin-Sheng, Zhang, Bo-Xiang, Hsieh, Tsung-Han, Hsu, Wayne, Ding, Jeak Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228695/
https://www.ncbi.nlm.nih.gov/pubmed/34201347
http://dx.doi.org/10.3390/cancers13122873