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Structural Constraint of Osteopontin Facilitates Efficient Binding to CD44

Since the original description in 1996, the interaction between the cytokine osteopontin (OPN) and the homing receptor CD44 has been extensively studied in cancer, inflammation, bone remodeling, and various other conditions. Alternative splicing and extensive posttranslational modifications by both...

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Detalles Bibliográficos
Autores principales: Fnu, Gulimirerouzi, Agrawal, Palak, Kundu, Gopal C., Weber, Georg F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228714/
https://www.ncbi.nlm.nih.gov/pubmed/34070790
http://dx.doi.org/10.3390/biom11060813