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Serum 5-Hydroxyindoleacetic Acid and Ratio of 5-Hydroxyindoleacetic Acid to Serotonin as Metabolomics Indicators for Acute Oxidative Stress and Inflammation in Vancomycin-Associated Acute Kidney Injury

The incidence of vancomycin-associated acute kidney injury (VAKI) varies from 5–43%, and early detection of VAKI is important in deciding whether to discontinue nephrotoxic agents. Oxidative stress is the main mechanism of VAKI, and serotonin (5-HT) and its metabolite 5-hydroxyindoleacetic acid (5-H...

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Detalles Bibliográficos
Autores principales: Lee, Hyun-Seung, Kim, Sang-Mi, Jang, Ja-Hyun, Park, Hyung-Doo, Lee, Soo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228749/
https://www.ncbi.nlm.nih.gov/pubmed/34199555
http://dx.doi.org/10.3390/antiox10060895