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Elucidating the Antimycobacterial Mechanism of Action of Decoquinate Derivative RMB041 Using Metabolomics

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), still remains one of the leading causes of death from a single infectious agent worldwide. The high prevalence of this disease is mostly ascribed to the rapid development of drug resistance to the current anti-TB drugs, exacerbated by la...

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Detalles Bibliográficos
Autores principales: Knoll, Kirsten E., Lindeque, Zander, Adeniji, Adetomiwa A., Oosthuizen, Carel B., Lall, Namrita, Loots, Du Toit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228794/
https://www.ncbi.nlm.nih.gov/pubmed/34200519
http://dx.doi.org/10.3390/antibiotics10060693