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Improper Remodeling of Organelles Deputed to Ca(2+) Handling and Aerobic ATP Production Underlies Muscle Dysfunction in Ageing

Proper skeletal muscle function is controlled by intracellular Ca(2+) concentration and by efficient production of energy (ATP), which, in turn, depend on: (a) the release and re-uptake of Ca(2+) from sarcoplasmic-reticulum (SR) during excitation–contraction (EC) coupling, which controls the contrac...

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Detalles Bibliográficos
Autores principales: Protasi, Feliciano, Pietrangelo, Laura, Boncompagni, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228829/
https://www.ncbi.nlm.nih.gov/pubmed/34201319
http://dx.doi.org/10.3390/ijms22126195