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Improper Remodeling of Organelles Deputed to Ca(2+) Handling and Aerobic ATP Production Underlies Muscle Dysfunction in Ageing
Proper skeletal muscle function is controlled by intracellular Ca(2+) concentration and by efficient production of energy (ATP), which, in turn, depend on: (a) the release and re-uptake of Ca(2+) from sarcoplasmic-reticulum (SR) during excitation–contraction (EC) coupling, which controls the contrac...
Autores principales: | Protasi, Feliciano, Pietrangelo, Laura, Boncompagni, Simona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228829/ https://www.ncbi.nlm.nih.gov/pubmed/34201319 http://dx.doi.org/10.3390/ijms22126195 |
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