Beneficial Effects of Mineralocorticoid Receptor Pathway Blockade against Endothelial Inflammation Induced by SARS-CoV-2 Spike Protein

Background: Vascular endothelial cells activation and dysfunction mediate inflammation and abnormal coagulation in COVID-19 patients. Mineralocorticoid receptor (MR) signaling and its downstream target Galectin-3 (Gal-3) are known to mediate cardiovascular inflammation and might be involved in the p...

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Detalles Bibliográficos
Autores principales: Jover, Eva, Matilla, Lara, Garaikoetxea, Mattie, Fernández-Celis, Amaya, Muntendam, Pieter, Jaisser, Frédéric, Rossignol, Patrick, López-Andrés, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228852/
https://www.ncbi.nlm.nih.gov/pubmed/34204890
http://dx.doi.org/10.3390/biomedicines9060639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228852/
https://www.ncbi.nlm.nih.gov/pubmed/34204890
http://dx.doi.org/10.3390/biomedicines9060639

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