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PBRM1 Cooperates with YTHDF2 to Control HIF-1α Protein Translation

PBRM1, a component of the chromatin remodeller SWI/SNF, is often deleted or mutated in human cancers, most prominently in renal cancers. Core components of the SWI/SNF complex have been shown to be important for the cellular response to hypoxia. Here, we investigated how PBRM1 controls HIF-1α activi...

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Detalles Bibliográficos
Autores principales: Shmakova, Alena, Frost, Mark, Batie, Michael, Kenneth, Niall S., Rocha, Sonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228889/
https://www.ncbi.nlm.nih.gov/pubmed/34200988
http://dx.doi.org/10.3390/cells10061425