Mapping the Intramolecular Communications among Different Glutamate Dehydrogenase States Using Molecular Dynamics

Glutamate dehydrogenase (GDH) is a ubiquitous enzyme that catalyzes the reversible oxidative deamination of glutamate to α-ketoglutarate. It acts as an important branch-point enzyme between carbon and nitrogen metabolisms. Due to the multifaceted roles of GDH in cancer, hyperinsulinism/hyperammonemi...

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Detalles Bibliográficos
Autores principales: Basith, Shaherin, Manavalan, Balachandran, Shin, Tae Hwan, Lee, Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228935/
https://www.ncbi.nlm.nih.gov/pubmed/34072154
http://dx.doi.org/10.3390/biom11060798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8228935/
https://www.ncbi.nlm.nih.gov/pubmed/34072154
http://dx.doi.org/10.3390/biom11060798

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