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Broad-Based Influenza-Specific CD8(+) T Cell Response without the Typical Immunodominance Hierarchy and Its Potential Implication

Syngeneic murine systems have pre-fixed MHC, making them an imperfect model for investigating the impact of MHC polymorphism on immunodominance in influenza A virus (IAV) infections. To date, there are few studies focusing on MHC allelic differences and its impact on immunodominance even though it i...

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Detalles Bibliográficos
Autores principales: Huang, Miaojuan, Xu, Rong, Triffon, Cristina, Mifsud, Nicole, Chen, Weisan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229067/
https://www.ncbi.nlm.nih.gov/pubmed/34198851
http://dx.doi.org/10.3390/v13061080