Prolonged Infusion of β-Lactams Decreases Mortality in Patients with Septic Shock: A Retrospective before-and-after Study

Septic shock substantially alters the pharmacokinetic properties of β-lactams with a subsequently high risk of insufficiently low serum concentrations and treatment failure. Considering their pharmacokinetic (PK)/pharmacodynamic (PD) index, prolonged infusions (PI) of β-lactams extend the time that...

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Detalles Bibliográficos
Autores principales: Richter, Daniel Christoph, Dietrich, Maximilian, Lalev, Lazar Detelinov, Schmitt, Felix C. F., Fiedler, Mascha Onida, Bruckner, Thomas, Stoerzinger, Dominic, Chiriac, Ute, Klein, Sabrina, Hackert, Thilo, Brenner, Thorsten, Brinkmann, Alexander, Weigand, Markus A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229114/
https://www.ncbi.nlm.nih.gov/pubmed/34201244
http://dx.doi.org/10.3390/antibiotics10060687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229114/
https://www.ncbi.nlm.nih.gov/pubmed/34201244
http://dx.doi.org/10.3390/antibiotics10060687

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