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Optimization of Vero Cells Grown on a Polymer Fiber Carrier in a Disposable Bioreactor for Inactivated Coxsackievirus A16 Vaccine Development

At present, there are no vaccines available for hand, foot, and mouth disease, which is caused by Coxsackie virus A16 (CVA16) infection. In the present study, we isolated epidemic strains of CVA16 and optimized the production of the virus in Vero cells. The system comprised growing the infected cell...

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Detalles Bibliográficos
Autores principales: Chen, Keda, Li, Chaonan, Wang, Ying, Shen, Zhenwei, Guo, Yikai, Li, Xiaoping, Zhang, Yanjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229131/
https://www.ncbi.nlm.nih.gov/pubmed/34200441
http://dx.doi.org/10.3390/vaccines9060613