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Optimization of Vero Cells Grown on a Polymer Fiber Carrier in a Disposable Bioreactor for Inactivated Coxsackievirus A16 Vaccine Development
At present, there are no vaccines available for hand, foot, and mouth disease, which is caused by Coxsackie virus A16 (CVA16) infection. In the present study, we isolated epidemic strains of CVA16 and optimized the production of the virus in Vero cells. The system comprised growing the infected cell...
Autores principales: | Chen, Keda, Li, Chaonan, Wang, Ying, Shen, Zhenwei, Guo, Yikai, Li, Xiaoping, Zhang, Yanjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229131/ https://www.ncbi.nlm.nih.gov/pubmed/34200441 http://dx.doi.org/10.3390/vaccines9060613 |
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