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Glutathione Deficiency during Early Postnatal Development Causes Schizophrenia-Like Symptoms and a Reduction in BDNF Levels in the Cortex and Hippocampus of Adult Sprague–Dawley Rats

Growing body of evidence points to dysregulation of redox status in the brain as an important factor in the pathogenesis of schizophrenia. The aim of our study was to evaluate the effects of l-buthionine-(S,R)-sulfoximine (BSO), a glutathione (GSH) synthesis inhibitor, and 1-[2-Bis(4-fluorophenyl)me...

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Detalles Bibliográficos
Autores principales: Lech, Marta Anna, Leśkiewicz, Monika, Kamińska, Kinga, Rogóż, Zofia, Lorenc-Koci, Elżbieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229148/
https://www.ncbi.nlm.nih.gov/pubmed/34201038
http://dx.doi.org/10.3390/ijms22126171