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Hydroquinone Exposure Worsens Rheumatoid Arthritis through the Activation of the Aryl Hydrocarbon Receptor and Interleukin-17 Pathways

Rheumatoid arthritis (RA) development is strongly associated with cigarette smoke exposure, which activates the aryl hydrocarbon receptor (AhR) as a trigger for Th17 inflammatory pathways. We previously demonstrated that the exposure to hydroquinone (HQ), one of the major compounds of cigarette tar,...

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Detalles Bibliográficos
Autores principales: Heluany, Cintia Scucuglia, Donate, Paula Barbim, Schneider, Ayda Henriques, Fabris, André Luis, Gomes, Renan Augusto, Villas-Boas, Isadora Maria, Tambourgi, Denise Vilarinho, da Silva, Tarcilia Aparecida, Trossini, Gustavo Henrique Goulart, Nalesso, Giovanna, Silveira, Eduardo Lani Volpe, Cunha, Fernando Queiroz, Farsky, Sandra Helena Poliselli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229175/
https://www.ncbi.nlm.nih.gov/pubmed/34200499
http://dx.doi.org/10.3390/antiox10060929