The AMPK/p27(Kip1) Pathway as a Novel Target to Promote Autophagy and Resilience in Aged Cells

Once believed to solely function as a cyclin-dependent kinase inhibitor, p27(Kip1) is now emerging as a critical mediator of autophagy, cytoskeletal dynamics, cell migration and apoptosis. During periods of metabolic stress, the subcellular location of p27(Kip1) largely dictates its function. Cytopl...

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Detalles Bibliográficos
Autores principales: McKay, Lauren K., White, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229180/
https://www.ncbi.nlm.nih.gov/pubmed/34201101
http://dx.doi.org/10.3390/cells10061430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229180/
https://www.ncbi.nlm.nih.gov/pubmed/34201101
http://dx.doi.org/10.3390/cells10061430

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