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Targeting HIF-1α Regulatory Pathways as a Strategy to Hamper Tumor-Microenvironment Interactions in CLL

SIMPLE SUMMARY: In chronic lymphocytic leukemia (CLL), the interplay between the neoplastic clone and the tumor microenvironment largely contributes to leukemia survival, tumor propagation and drug resistance. A better understanding of the molecular circuits sustaining the biological effects of this...

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Detalles Bibliográficos
Autores principales: Vitale, Candida, Griggio, Valentina, Riganti, Chiara, Todaro, Maria, Kopecka, Joanna, Jones, Rebecca, Salvetti, Chiara, Boccellato, Elia, Perutelli, Francesca, Voena, Claudia, Godio, Laura, Boccadoro, Mario, Coscia, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229189/
https://www.ncbi.nlm.nih.gov/pubmed/34207596
http://dx.doi.org/10.3390/cancers13122883