Cargando…
Targeting HIF-1α Regulatory Pathways as a Strategy to Hamper Tumor-Microenvironment Interactions in CLL
SIMPLE SUMMARY: In chronic lymphocytic leukemia (CLL), the interplay between the neoplastic clone and the tumor microenvironment largely contributes to leukemia survival, tumor propagation and drug resistance. A better understanding of the molecular circuits sustaining the biological effects of this...
Autores principales: | Vitale, Candida, Griggio, Valentina, Riganti, Chiara, Todaro, Maria, Kopecka, Joanna, Jones, Rebecca, Salvetti, Chiara, Boccellato, Elia, Perutelli, Francesca, Voena, Claudia, Godio, Laura, Boccadoro, Mario, Coscia, Marta |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229189/ https://www.ncbi.nlm.nih.gov/pubmed/34207596 http://dx.doi.org/10.3390/cancers13122883 |
Ejemplares similares
-
Immune Dysfunctions and Immune-Based Therapeutic Interventions in Chronic Lymphocytic Leukemia
por: Griggio, Valentina, et al.
Publicado: (2020) -
Autoimmune Complications in Chronic Lymphocytic Leukemia in the Era of Targeted Drugs
por: Vitale, Candida, et al.
Publicado: (2020) -
Impact of Immune Parameters and Immune Dysfunctions on the Prognosis of Patients with Chronic Lymphocytic Leukemia
por: Vitale, Candida, et al.
Publicado: (2021) -
Anti-tumor activity of selinexor in combination with antineoplastic agents in chronic lymphocytic leukemia
por: Vitale, Candida, et al.
Publicado: (2023) -
Simvastatin and downstream inhibitors circumvent constitutive and stromal cell-induced resistance to doxorubicin in IGHV unmutated CLL cells
por: Rigoni, Micol, et al.
Publicado: (2015)