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Pharmacokinetics-Driven Evaluation of the Antioxidant Activity of Curcuminoids and Their Major Reduced Metabolites—A Medicinal Chemistry Approach

Curcuminoids are the main bioactive components of the well-known Asian spice and traditional medicine turmeric. Curcuminoids have poor chemical stability and bioavailability; in vivo they are rapidly metabolized to a set of bioreduced derivatives and/or glucuronide and sulfate conjugates. The reduce...

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Detalles Bibliográficos
Autores principales: Girst, Gábor, Ötvös, Sándor B., Fülöp, Ferenc, Balogh, György T., Hunyadi, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229286/
https://www.ncbi.nlm.nih.gov/pubmed/34200647
http://dx.doi.org/10.3390/molecules26123542