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Optimization of Collagen Chemical Crosslinking to Restore Biocompatibility of Tissue-Engineered Scaffolds

Collagen scaffolds, one of the most used biomaterials in corneal tissue engineering, are frequently crosslinked to improve mechanical properties, enzyme tolerance, and thermal stability. Crosslinkers such as 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC) are compatible with tissu...

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Detalles Bibliográficos
Autores principales: Islam, Mohammad Mirazul, AbuSamra, Dina B., Chivu, Alexandru, Argüeso, Pablo, Dohlman, Claes H., Patra, Hirak K., Chodosh, James, González-Andrades, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229326/
https://www.ncbi.nlm.nih.gov/pubmed/34204956
http://dx.doi.org/10.3390/pharmaceutics13060832