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Genetic Dissection of Vps13 Regulation in Yeast Using Disease Mutations from Human Orthologs

The VPS13 family of proteins have emerged as key players in intracellular lipid transport and human health. Humans have four different VPS13 orthologs, the dysfunction of which leads to different diseases. Yeast has a single VPS13 gene, which encodes a protein that localizes to multiple different me...

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Detalles Bibliográficos
Autores principales: Park, Jae-Sook, Hollingsworth, Nancy M., Neiman, Aaron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229349/
https://www.ncbi.nlm.nih.gov/pubmed/34201352
http://dx.doi.org/10.3390/ijms22126200