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Scaffold Hopping of α-Rubromycin Enables Direct Access to FDA-Approved Cromoglicic Acid as a SARS-CoV-2 M(Pro) Inhibitor

The COVID-19 pandemic is still active around the globe despite the newly introduced vaccines. Hence, finding effective medications or repurposing available ones could offer great help during this serious situation. During our anti-COVID-19 investigation of microbial natural products (MNPs), we came...

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Detalles Bibliográficos
Autores principales: Alhadrami, Hani A., Sayed, Ahmed M., Al-Khatabi, Heba, Alhakamy, Nabil A., Rateb, Mostafa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229550/
https://www.ncbi.nlm.nih.gov/pubmed/34198933
http://dx.doi.org/10.3390/ph14060541