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Inhibition of the Heat Shock Protein A (HSPA) Family Potentiates the Anticancer Effects of Manumycin A

Manumycin A (MA) is a well-tolerated natural antibiotic showing pleiotropic anticancer effects in various preclinical in vitro and in vivo models. Anticancer drugs may themselves act as stressors to induce the cellular adaptive mechanism that can minimize their cytotoxicity. Heat shock proteins (HSP...

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Detalles Bibliográficos
Autores principales: Sojka, Damian Robert, Hasterok, Sylwia, Vydra, Natalia, Toma-Jonik, Agnieszka, Wieczorek, Anna, Gogler-Pigłowska, Agnieszka, Scieglinska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229576/
https://www.ncbi.nlm.nih.gov/pubmed/34200371
http://dx.doi.org/10.3390/cells10061418