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17-β Estradiol Rescued Immature Rat Brain against Glutamate-Induced Oxidative Stress and Neurodegeneration via Regulating Nrf2/HO-1 and MAP-Kinase Signaling Pathway

Dysregulated glutamate signaling, leading to neuronal excitotoxicity and death, has been associated with neurodegenerative pathologies. 17β-estradiol (E2) is a human steroid hormone having a role in reproduction, sexual maturation, brain health and biological activities. The study aimed to explain t...

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Detalles Bibliográficos
Autores principales: Khan, Ibrahim, Saeed, Kamran, Jo, Min Gi, Kim, Myeong Ok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229583/
https://www.ncbi.nlm.nih.gov/pubmed/34206065
http://dx.doi.org/10.3390/antiox10060892