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Induction of Stress-Induced Renal Cellular Senescence In Vitro: Impact of Mouse Strain Genetic Diversity

Cellular senescence, a stress-induced state of irreversible cell cycle arrest, is associated with organ dysfunction and age-related disease. While immortalized cell lines bypass key pathways of senescence, important mechanisms of cellular senescence can be studied in primary cells. Primary tubular e...

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Detalles Bibliográficos
Autores principales: Liao, Chieh Ming, Wulfmeyer, Vera Christine, Swallow, Maxine, Falk, Christine Susanne, Haller, Hermann, Korstanje, Ron, Melk, Anette, Schmitt, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229707/
https://www.ncbi.nlm.nih.gov/pubmed/34201242
http://dx.doi.org/10.3390/cells10061437