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Selection of Human Cytomegalovirus Mutants with Resistance against PDGFRα-Derived Entry Inhibitors

The human cytomegalovirus (HCMV) infects fibroblasts via an interaction of its envelope glycoprotein gO with the cellular platelet-derived growth factor receptor alpha (PDGFRα), and soluble derivatives of this receptor can inhibit viral entry. We aimed to select mutants with resistance against PDGFR...

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Detalles Bibliográficos
Autores principales: Laib Sampaio, Kerstin, Lutz, Carolin, Engels, Rebecca, Stöhr, Dagmar, Sinzger, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229732/
https://www.ncbi.nlm.nih.gov/pubmed/34201364
http://dx.doi.org/10.3390/v13061094