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Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization

NK cells are the first line of defense against viruses and malignant cells, and their natural functionality makes these cells a promising candidate for cancer cell therapy. The genetic modifications of NK cells, allowing them to overcome some of their inherent limitations, such as low proliferative...

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Detalles Bibliográficos
Autores principales: Streltsova, Maria A., Ustiuzhanina, Maria O., Barsov, Eugene V., Kust, Sofya A., Velichinskii, Rodion A., Kovalenko, Elena I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229856/
https://www.ncbi.nlm.nih.gov/pubmed/34207853
http://dx.doi.org/10.3390/biomedicines9060662