Cargando…

Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization

NK cells are the first line of defense against viruses and malignant cells, and their natural functionality makes these cells a promising candidate for cancer cell therapy. The genetic modifications of NK cells, allowing them to overcome some of their inherent limitations, such as low proliferative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Streltsova, Maria A., Ustiuzhanina, Maria O., Barsov, Eugene V., Kust, Sofya A., Velichinskii, Rodion A., Kovalenko, Elena I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229856/ https://www.ncbi.nlm.nih.gov/pubmed/34207853 http://dx.doi.org/10.3390/biomedicines9060662

Ejemplares similares

The Biological Role and Therapeutic Potential of NK Cells in Hematological and Solid Tumors
por: Velichinskii, Rodion A., et al.
Publicado: (2021)

Multiple Actions of Telomerase Reverse Transcriptase in Cell Death Regulation
por: Palamarchuk, Anastasia I., et al.
Publicado: (2023)

Phenotypic Changes in T and NK Cells Induced by Sputnik V Vaccination
por: Boyko, Anna A., et al.
Publicado: (2023)

Characterization of human telomerase reverse transcriptase immortalized anterior cruciate ligament cell lines
por: Prager, Patrick, et al.
Publicado: (2019)

Increased Susceptibility of the CD57(−) NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response
por: Palamarchuk, Anastasia I., et al.
Publicado: (2021)

HLA-DR-Positive NK Cells Expand in Response to Mycobacterium Tuberculosis Antigens and Mediate Mycobacteria-Induced T Cell Activation
por: Kust, Sofya A., et al.
Publicado: (2021)

Telomerase reverse transcriptase and neurodegenerative diseases
por: Yu, Xin, et al.
Publicado: (2023)

Telomerase reverse transcriptase moonlights: Therapeutic targets beyond telomerase
por: Maida, Yoshiko, et al.
Publicado: (2015)

Coordinated Loss and Acquisition of NK Cell Surface Markers Accompanied by Generalized Cytokine Dysregulation in COVID-19
por: Ustiuzhanina, Maria O., et al.
Publicado: (2023)

Expression of Telomerase Reverse Transcriptase in Psoriatic Lesional Skin
por: Mahmoud, Moushira A., et al.
Publicado: (2006)

Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility
por: McAloney, Camille A, et al.
Publicado: (2014)

Telomerase reverse transcriptase in the regulation of gene expression
por: Zhou, Junzhi, et al.
Publicado: (2014)

Telomerase Reverse Transcriptase Regulates microRNAs
por: Lassmann, Timo, et al.
Publicado: (2015)

Implications of telomerase reverse transcriptase in tumor metastasis
por: Zou, Yongkang, et al.
Publicado: (2020)

Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors
por: Burgess, J. K., et al.
Publicado: (2018)

Correction to: Polymorphisms within the Telomerase Reverse Transcriptase gene (TERT) in four breeds of dogs selected for difference in lifespan and cancer susceptibility
por: McAloney, Camille A., et al.
Publicado: (2021)

Expression of telomerase-associated protein 1 and telomerase reverse transcriptase in hepatocellular carcinoma
por: Toshikuni, N, et al.
Publicado: (2000)

Expression of Telomerase Catalytic Component, Telomerase Reverse Transcriptase, in Human Gastric Carcinomas
por: Yasui, Wataru, et al.
Publicado: (1998)

Regulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic Mechanisms
por: Lewis, Kayla A., et al.
Publicado: (2016)

Usefulness of Immunological Detection of the Human Telomerase Reverse Transcriptase
por: Volpi, Annalisa, et al.
Publicado: (2005)

Human Specific Regulation of the Telomerase Reverse Transcriptase Gene
por: Zhang, Fan, et al.
Publicado: (2016)

Transcriptional Regulation of Telomerase Reverse Transcriptase (TERT) by MYC
por: Khattar, Ekta, et al.
Publicado: (2017)

Diverse regulatory manners of human telomerase reverse transcriptase
por: Jie, Meng-Meng, et al.
Publicado: (2019)

Expression of telomerase reverse transcriptase in peripheral T‐cell lymphoma
por: Arakawa, Fumiko, et al.
Publicado: (2021)

Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase
por: Petrova, Olga A, et al.
Publicado: (2018)

Clinical Significance of Telomerase Reverse-Transcriptase Promoter Mutations in Hepatocellular Carcinoma
por: Pezzuto, Francesca, et al.
Publicado: (2021)

The telomerase reverse transcriptase elongates reversed replication forks at telomeric repeats
por: Huda, Armela, et al.
Publicado: (2023)

Immunohistochemical expression of h-telomerase reverse transcriptase in canine and feline meningiomas
por: Mandrioli, Luciana, et al.
Publicado: (2007)

Telomerase Reverse Transcriptase (TERT) Regulation in Thyroid Cancer: A Review
por: McKelvey, Brittany A., et al.
Publicado: (2020)

Immortalization and Characterization of Porcine Macrophages That Had Been Transduced with Lentiviral Vectors Encoding the SV40 Large T Antigen and Porcine Telomerase Reverse Transcriptase
por: Takenouchi, Takato, et al.
Publicado: (2017)

The Emerging Role of Telomerase Reverse Transcriptase in Mitochondrial DNA Metabolism
por: Gordon, Donna M., et al.
Publicado: (2010)

Telomerase Reverse Transcriptase (TERT) in Action: Cross-Talking with Epigenetics
por: Yuan, Xiaotian, et al.
Publicado: (2019)

Mitochondrial Telomerase Reverse Transcriptase, a Target for Cardiovascular Disease?
por: Torimoto, Keiichi, et al.
Publicado: (2022)

Deciphering the Functions of Telomerase Reverse Transcriptase in Head and Neck Cancer
por: Yeh, Tsung-Jang, et al.
Publicado: (2023)

Human Telomerase Reverse Transcriptase (hTERT) Q169 Is Essential for Telomerase Function In Vitro and In Vivo
por: Wyatt, Haley D. M., et al.
Publicado: (2009)

Hedgehog Signaling Regulates Telomerase Reverse Transcriptase in Human Cancer Cells
por: Mazumdar, Tapati, et al.
Publicado: (2013)

Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma
por: Sze, Karen Man‐Fong, et al.
Publicado: (2020)

Influence of Human Telomerase Reverse Transcriptase Mutation on the Aggressiveness and Recurrence in Meningiomas
por: Sahin, Balkan, et al.
Publicado: (2021)

Reactivation of telomerase reverse transcriptase expression in cancer: the role of TERT promoter mutations
por: Tornesello, Maria Lina, et al.
Publicado: (2023)

Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes
por: Wu, Robert Alexander, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_l7h7vouthg1hf5vle3ikbkf74t