Elaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity

The natural product elaiophylin is a macrodiolide with a broad range of biological activities. However, no direct target of elaiophylin in eukaryotes has been described so far, which hinders a systematic explanation of its astonishing activity range. We recently showed that the related conglobatin A...

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Detalles Bibliográficos
Autores principales: Siddiqui, Farid A., Vukic, Vladimir, Salminen, Tiina A., Abankwa, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229862/
https://www.ncbi.nlm.nih.gov/pubmed/34199986
http://dx.doi.org/10.3390/biom11060836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229862/
https://www.ncbi.nlm.nih.gov/pubmed/34199986
http://dx.doi.org/10.3390/biom11060836

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