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Single-Cell Transcriptional Heterogeneity of Lymphatic Endothelial Cells in Normal and Inflamed Murine Lymph Nodes

The lymphatic system plays a crucial role in immunity and lymph nodes (LNs) undergo drastic remodeling during inflammation. Here, we used single-cell RNA sequencing to investigate transcriptional changes in lymphatic endothelial cells (LECs) in LNs draining naïve and inflamed skin. We found that sub...

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Detalles Bibliográficos
Autores principales: Sibler, Eliane, He, Yuliang, Ducoli, Luca, Keller, Nadja, Fujimoto, Noriki, Dieterich, Lothar C., Detmar, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229892/
https://www.ncbi.nlm.nih.gov/pubmed/34199492
http://dx.doi.org/10.3390/cells10061371