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Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice

Mitoxantrone (MTX) is a pharmaceutical drug used in the treatment of several cancers and refractory multiple sclerosis (MS). Despite its therapeutic value, adverse effects may be severe, namely the frequently reported cardiotoxicity, whose mechanisms need further research. This work aimed to assess...

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Detalles Bibliográficos
Autores principales: Reis-Mendes, Ana, Dores-Sousa, José Luís, Padrão, Ana Isabel, Duarte-Araújo, Margarida, Duarte, José Alberto, Seabra, Vítor, Gonçalves-Monteiro, Salomé, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229902/
https://www.ncbi.nlm.nih.gov/pubmed/34073506
http://dx.doi.org/10.3390/ph14060510