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Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice
Mitoxantrone (MTX) is a pharmaceutical drug used in the treatment of several cancers and refractory multiple sclerosis (MS). Despite its therapeutic value, adverse effects may be severe, namely the frequently reported cardiotoxicity, whose mechanisms need further research. This work aimed to assess...
Autores principales: | Reis-Mendes, Ana, Dores-Sousa, José Luís, Padrão, Ana Isabel, Duarte-Araújo, Margarida, Duarte, José Alberto, Seabra, Vítor, Gonçalves-Monteiro, Salomé, Remião, Fernando, Carvalho, Félix, Sousa, Emília, Bastos, Maria Lourdes, Costa, Vera Marisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229902/ https://www.ncbi.nlm.nih.gov/pubmed/34073506 http://dx.doi.org/10.3390/ph14060510 |
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