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The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction
Ras and Rho proteins are GTP-regulated molecular switches that control multiple signaling pathways in eukaryotic cells. Ras was among the first identified oncogenes, and it appears mutated in many forms of human cancer. It mainly promotes proliferation and survival through the MAPK pathway and the P...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8229961/ https://www.ncbi.nlm.nih.gov/pubmed/34071831 http://dx.doi.org/10.3390/genes12060819 |