Immunomodulatory mAbs as Tools to Investigate on Cis-Interaction of PD-1/PD-L1 on Tumor Cells and to Set Up Methods for Early Screening of Safe and Potent Combinatorial Treatments

SIMPLE SUMMARY: A novel challenge in cancer immunotherapy is the identification of the most potent combinations of immunomodulatory mAbs that are capable of maximizing therapeutic benefits while minimizing irAEs. We set up an in vitro system to quickly predict the efficacy and eventual cardiotoxic s...

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Detalles Bibliográficos
Autores principales: Vetrei, Cinzia, Passariello, Margherita, Froechlich, Guendalina, Rapuano Lembo, Rosa, Zambrano, Nicola, De Lorenzo, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230074/
https://www.ncbi.nlm.nih.gov/pubmed/34201082
http://dx.doi.org/10.3390/cancers13122858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230074/
https://www.ncbi.nlm.nih.gov/pubmed/34201082
http://dx.doi.org/10.3390/cancers13122858

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