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Culture of Mycobacterium smegmatis in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis

During tuberculosis, Mycobacterium uses host macrophage cholesterol as a carbon and energy source. To mimic these conditions, Mycobacterium smegmatis can be cultured in minimal medium (MM) to induce cholesterol consumption in vitro. During cultivation, M. smegmatis consumes MM cholesterol and change...

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Detalles Bibliográficos
Autores principales: de Lima, Jaqueline Batista, da Silva Fonseca, Lana Patricia, Xavier, Luciana Pereira, de Matos Macchi, Barbarella, Cassoli, Juliana Silva, da Silva, Edilene Oliveira, da Silva Valadares, Rafael Borges, do Nascimento, José Luiz Martins, Santos, Agenor Valadares, de Sena, Chubert Bernardo Castro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230116/
https://www.ncbi.nlm.nih.gov/pubmed/34071265
http://dx.doi.org/10.3390/pathogens10060662