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Culture of Mycobacterium smegmatis in Different Carbon Sources to Induce In Vitro Cholesterol Consumption Leads to Alterations in the Host Cells after Infection: A Macrophage Proteomics Analysis
During tuberculosis, Mycobacterium uses host macrophage cholesterol as a carbon and energy source. To mimic these conditions, Mycobacterium smegmatis can be cultured in minimal medium (MM) to induce cholesterol consumption in vitro. During cultivation, M. smegmatis consumes MM cholesterol and change...
Autores principales: | de Lima, Jaqueline Batista, da Silva Fonseca, Lana Patricia, Xavier, Luciana Pereira, de Matos Macchi, Barbarella, Cassoli, Juliana Silva, da Silva, Edilene Oliveira, da Silva Valadares, Rafael Borges, do Nascimento, José Luiz Martins, Santos, Agenor Valadares, de Sena, Chubert Bernardo Castro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230116/ https://www.ncbi.nlm.nih.gov/pubmed/34071265 http://dx.doi.org/10.3390/pathogens10060662 |
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