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Group A Streptococcus-Induced Activation of Human Plasminogen Is Required for Keratinocyte Wound Retraction and Rapid Clot Dissolution

Invasive outcomes of Group A Streptococcus (GAS) infections that involve damage to skin and other tissues are initiated when these bacteria colonize and disseminate via an open wound to gain access to blood and deeper tissues. Two critical GAS virulence factors, Plasminogen-Associated M-Protein (PAM...

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Detalles Bibliográficos
Autores principales: Vu, Henry M., Hammers, Daniel E., Liang, Zhong, Nguyen, Gabrielle L., Benz, Mary E., Moran, Thomas E., Higashi, Dustin L., Park, Claudia J., Ayinuola, Yetunde A., Donahue, Deborah L., Flores-Mireles, Ana L., Ploplis, Victoria A., Castellino, Francis J., Lee, Shaun W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230121/
https://www.ncbi.nlm.nih.gov/pubmed/34179133
http://dx.doi.org/10.3389/fcvm.2021.667554