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Irinotecan (CPT-11) Canonical Anti-Cancer Drug Can also Modulate Antiviral and Pro-Inflammatory Responses of Primary Human Synovial Fibroblasts

Alphaviruses are a group of arboviruses that generate chronic inflammatory rheumatisms in humans. Currently, no approved vaccines or antiviral therapies are available to prevent or treat alphavirus-induced diseases. The aim of this study was to evaluate the repositioning of the anti-cancer molecule...

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Detalles Bibliográficos
Autores principales: Dobi, Anthony, Gasque, Philippe, Guiraud, Pascale, Selambarom, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230279/
https://www.ncbi.nlm.nih.gov/pubmed/34201243
http://dx.doi.org/10.3390/cells10061431