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Improving the Pharmacological Properties of Ciclopirox for Its Use in Congenital Erythropoietic Porphyria

Congenital erythropoietic porphyria (CEP), also known as Günther’s disease, results from a deficient activity in the fourth enzyme, uroporphyrinogen III synthase (UROIIIS), of the heme pathway. Ciclopirox (CPX) is an off-label drug, topically prescribed as an antifungal. It has been recently shown t...

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Detalles Bibliográficos
Autores principales: Bernardo-Seisdedos, Ganeko, Charco, Jorge M., SanJuan, Itxaso, García-Martínez, Sandra, Urquiza, Pedro, Eraña, Hasier, Castilla, Joaquín, Millet, Oscar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230281/
https://www.ncbi.nlm.nih.gov/pubmed/34071291
http://dx.doi.org/10.3390/jpm11060485