The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling

Myocardial injury is associated with inflammation and fibrosis. Cardiac myosin-binding protein-C (cMyBP-C) is cleaved by µ-calpain upon myocardial injury, releasing C0-C1f, an N-terminal peptide of cMyBP-C. Previously, we reported that the presence of C0-C1f is pathogenic within cardiac tissue and i...

Descripción completa

Detalles Bibliográficos
Autores principales: Yogeswaran, Athiththan, Troidl, Christian, McNamara, James W., Wilhelm, Jochen, Truschel, Theresa, Widmann, Laila, Aslam, Muhammad, Hamm, Christian W., Sadayappan, Sakthivel, Lipps, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230336/
https://www.ncbi.nlm.nih.gov/pubmed/34073556
http://dx.doi.org/10.3390/cells10061326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230336/
https://www.ncbi.nlm.nih.gov/pubmed/34073556
http://dx.doi.org/10.3390/cells10061326

Ejemplares similares