Wnt-Signaling Inhibitor Wnt-C59 Suppresses the Cytokine Upregulation in Multiple Organs of Lipopolysaccharide-Induced Endotoxemic Mice via Reducing the Interaction between β-Catenin and NF-κB

Sepsis is characterized by multiple-organ dysfunction caused by the dysregulated host response to infection. Until now, however, the role of the Wnt signaling has not been fully characterized in multiple organs during sepsis. This study assessed the suppressive effect of a Wnt signaling inhibitor, W...

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Detalles Bibliográficos
Autores principales: Jang, Jaewoong, Song, Jaewon, Sim, Inae, Kwon, Young V., Yoon, Yoosik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230366/
https://www.ncbi.nlm.nih.gov/pubmed/34200709
http://dx.doi.org/10.3390/ijms22126249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8230366/
https://www.ncbi.nlm.nih.gov/pubmed/34200709
http://dx.doi.org/10.3390/ijms22126249

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